Clayton M. Smith, M.D., FACP

Clayton M. Smith, M.D.

Clayton M. Smith, M.D., FACP

550 South Jackson Street, Ste. A3K00
Louisville, KY 40202

502-852-7040 - Academic Office
502-588-4500 -
Patient Appointments


Clinical Expertise
Internal Medicine; Primary Care; Medical Education; LGBTQ Health


Board Certifications

  • American Board of Internal Medicine -
    Internal Medicine

Education and Training

  • Medical School: University of Miami Miller School of Medicine
  • Residency: University of Louisville Hospital

Featured Publications

  • Spindel JF, Pokrywa S, Elder N, Smith C. The environment has effects on infrared temperature screening for COVID-19 infection. Am J Infect Control. 2021 Nov;49(11):1445-1447. doi: 10.1016/j.ajic.2021.08.002. Epub 2021 Aug 11. PMID: 34389316; PMCID: PMC8354813.
  • Reed K, Reynolds SB, Smith C. The First Case of Ignatzschineria ureiclastica/larvae in the United States Presenting as a Myiatic Wound Infection. Cureus. 2021 Apr 16;13(4):e14518. doi: 10.7759/cureus.14518. PMID: 34007769; PMCID: PMC8126268.