More than 40 research scientists and engineers from diverse disciplines come together in the new 106,000 square foot research facility on the University of Louisville's main campus. The Belknap Research Building houses one of the premier multidisciplinary research facilities in the region. The 10,000 square ft. multi-user cleanroom core facility is the signature research lab in the building. This "cleanroom" allows UofL researchers to use a wide range of equipment to fabricate, package, and test various microelectronic devices and circuits.

Other key facilities within the structure are biological, chemical and engineering research laboratories, conference and “break” rooms and a multipurpose 100-seat capacity area with audio-visual capabilities. The Center for Regulatory, Environmental and Analytical Metabolomics (CREAM), based in the Department of Chemistry and with faculty from both Arts and Sciences and the Health Sciences Campus is housed in this facility. Scientists from the College of Arts and Sciences with expertise in molecular, cellular and structural biology and synthetic, analytical and biochemistry rub shoulders with engineers with specialties in MEMS, bioMEMS, nanotechnology, electrooptics, biomechanics, bioengineering, microfabrication, and theoretical and applied physics. Together they work at the interfaces of biology, chemistry, engineering and medicine from which advances in nanomedicine, pharmaceutical design and other fields will emerge. To enhance multidisciplinary research, the placement of laboratories are located so that faculty with similar interests, regardless of discipline, will be in close proximity..